[Hakulyte]

Note that hand movements circulate all the way through your arms, shoulders and eventually your neck.

I personally never really had issues with hands, but my shoulder eventually got misaligned a bit from having a hand posture that wasn't optimal.

It forced me to stop using close setups and priorize more spread apart ones for comfort and also my left hand.

I used to play with like O,P, Delete, End.
Now I use W,E,7,8 (numpad). I also had to disable numlock.

Closer setups gave me more control overall, but it was also taxing physically. Not worth it.